Endocrine Abstracts

Introduction: Obesity is associated with increased cardiovascular disease (CVD) risk but the underlying pathways are unclear. Extracellular vesicles (EVs) are circulating submicron particles containing proteins, enzymes and mRNA of their donor cells. They could mediate some of these risks by paracrine actions in target cells.Aims: To compare the concentration and characteristics of circulating EVs from healthy volunteers (HV)...

Introduction: Obesity is associated with increased cardiovascular disease (CVD) risk but the underlying pathways are unclear. Extracellular vesicles (EVs) are circulating submicron particles containing proteins, enzymes and mRNA of their donor cells. They could mediate some of these risks by paracrine actions in target cells.Aims: To compare the concentration and characteristics of circulating EVs from healthy volunteers (HV)...

Introduction: Extracellular vesicles (EVs) are submicron vesicles released by most cells. They contain protein, enzymes and microRNA of the donor cells and are believed to play a role in paracrine communication. Circulating EVs might reflect heightened immune/inflammatory status in obese individuals and play a role in initiation/modulation of chronic low grade inflammation associated with obesity.Aims: To compare circulating plasma EVs between healthy vo...